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Robert D Simari Selected Research

Myocardial Infarction

1/2018Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit+ Cardiac Stem Cells As Regenerative Therapy for Heart Failure).
1/2018TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis.
4/2017Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).
1/2016Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial.
1/2015Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial.
10/2014Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.
5/2014Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network.
4/2013Bone marrow-derived cell therapy after myocardial infarction.
12/2012Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial.
12/2012Osteocalcin positive CD133+/CD34-/KDR+ progenitor cells as an independent marker for unstable atherosclerosis.
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Robert D Simari Research Topics

Disease

15Myocardial Infarction
01/2018 - 07/2007
11Heart Failure
11/2020 - 05/2004
9Cardiovascular Diseases (Cardiovascular Disease)
08/2021 - 03/2002
8Thrombosis (Thrombus)
01/2021 - 09/2004
8Coronary Artery Disease (Coronary Atherosclerosis)
01/2018 - 04/2007
7Left Ventricular Dysfunction
10/2014 - 07/2007
6Vascular Diseases (Vascular Disease)
04/2015 - 09/2004
5Fibrosis (Cirrhosis)
01/2018 - 07/2010
4Vascular System Injuries
01/2021 - 12/2006
4Cardiomyopathies (Cardiomyopathy)
11/2020 - 01/2016
4Hypertension (High Blood Pressure)
01/2019 - 04/2010
4Myocardial Ischemia (Ischemic Heart Diseases)
01/2015 - 01/2008
4Atherosclerosis
12/2012 - 09/2003
3Cicatrix (Scar)
01/2021 - 07/2007
3Wounds and Injuries (Trauma)
01/2021 - 03/2005
3Hemorrhage
01/2021 - 01/2010
3ST Elevation Myocardial Infarction
01/2018 - 12/2012
3Infarction (Infarctions)
01/2015 - 03/2006
3Atherosclerotic Plaque (Atheroma)
07/2014 - 06/2007
3Inflammation (Inflammations)
05/2013 - 07/2010
3Ischemia
03/2012 - 03/2009
3Vascular Remodeling
01/2012 - 04/2003
3Neointima
02/2011 - 04/2003
2Heart Diseases (Heart Disease)
02/2016 - 07/2010
2Vascular Calcification
12/2012 - 12/2012
2Hypertrophy
07/2010 - 05/2004
1Intermittent Claudication
04/2017
1Stroke (Strokes)
04/2017
1Peripheral Arterial Disease
04/2017
1Infections
02/2016
1Endocarditis
02/2016
1Diabetes Mellitus
04/2014
1Renal Artery Obstruction (Renal Artery Stenosis)
04/2013
1Atrophy
04/2013
1Body Weight (Weight, Body)
05/2012
1Chronic Limb-Threatening Ischemia
05/2012
1Melanoma (Melanoma, Malignant)
01/2012
1Hypoxia (Hypoxemia)
07/2010
1Pulmonary Hypertension
07/2010
1Atrial Fibrillation
04/2010
1Ventricular Remodeling
01/2010

Drug/Important Bio-Agent (IBA)

10lipoprotein-associated coagulation inhibitor (TFPI)IBA
01/2021 - 04/2003
4Biomarkers (Surrogate Marker)IBA
08/2021 - 10/2014
3FibrinIBA
01/2021 - 07/2010
3Hemostatics (Antihemorrhagics)IBA
01/2021 - 09/2004
3OsteocalcinIBA
02/2015 - 12/2012
3Apolipoproteins E (ApoE)IBA
07/2014 - 06/2007
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2013 - 08/2004
2omega-Chloroacetophenone (Mace)IBA
01/2021 - 01/2018
2AnthracyclinesIBA
11/2020 - 01/2018
2salicylhydroxamic acid (SHAM)IBA
05/2012 - 07/2010
2ferric chlorideIBA
09/2010 - 09/2004
2Acetates (Acetic Acid Esters)FDA Link
09/2010 - 07/2010
2Desoxycorticosterone (Deoxycorticosterone)IBA
09/2010 - 07/2010
2Thromboplastin (Tissue Factor)IBA
07/2010 - 01/2010
2ApolipoproteinsIBA
09/2009 - 06/2007
2Pregnancy-Associated Plasma Protein-A (PAPP-A)IBA
06/2007 - 12/2006
2Metalloproteases (Metalloproteinases)IBA
06/2007 - 12/2006
2Insulin-Like Growth Factor I (IGF-1)IBA
06/2007 - 12/2006
2Phenobarbital (Luminal)FDA Link
10/2004 - 04/2003
1ThrombinFDA Link
01/2021
1pro-brain natriuretic peptide (1-76)IBA
01/2018
1Aldehyde DehydrogenaseIBA
04/2017
1Coloring Agents (Dyes)IBA
02/2016
1Hematoxylin (Haematoxylon)IBA
02/2016
1Eosine Yellowish-(YS) (Eosin)IBA
02/2016
1C-Reactive ProteinIBA
01/2016
1Alkaline PhosphataseIBA
02/2015
1Warfarin (Coumadin)FDA LinkGeneric
02/2015
1oxidized low density lipoproteinIBA
07/2014
1SB 203580IBA
04/2013
1p38 Mitogen-Activated Protein KinasesIBA
04/2013
1Vascular Endothelial Growth Factor CIBA
01/2012
1MorpholinosIBA
01/2012
1Desoxycorticosterone Acetate (DOCA)FDA Link
09/2010
1Hydroxysteroid DehydrogenasesIBA
07/2010
1OsteopontinIBA
07/2010
1MineralocorticoidsIBA
07/2010
1SaltsIBA
07/2010
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
07/2010
12'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
07/2010
1CreatinineIBA
04/2010
1CholesterolIBA
09/2009
1ReninIBA
07/2009
1Peptides (Polypeptides)IBA
07/2009
1AngiotensinsIBA
07/2009
1acetyl-LDLIBA
05/2009
1Insulin-Like PeptidesIBA
06/2007

Therapy/Procedure

19Therapeutics
01/2018 - 03/2002
17Cell- and Tissue-Based Therapy (Cell Therapy)
11/2020 - 07/2007
5Percutaneous Coronary Intervention
01/2015 - 01/2010
3Transplantation
01/2016 - 11/2011
2Stents
01/2018 - 02/2011
2Injections
01/2016 - 04/2012
2Coronary Artery Bypass (Coronary Artery Bypass Surgery)
12/2012 - 03/2009
2Cell Transplantation
01/2012 - 07/2007
1Punctures
01/2021
1Bioreactors (Bioreactor)
01/2019
1Surgical Amputation (Amputations)
04/2017
1Nephrectomy
07/2010